Carbamic Acid

Carbamic Acid

SCHEMBL7455331

NC(=O)O.NC(=O)c1ccccc1CC(N)CO

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.44
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41
SLC7A5 Q01650 1/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NOS3 P29474 2/20 0.39
NOS1 P29475 2/20 0.39
NOS2 P35228 2/20 0.39
EPHX1 P07099 2/20 0.38
METAP2 P50579 1/20 0.38
CTNNB1 P35222 1/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL7780891 1.00 BCAT2 (0.44) BCAT2ALPIPKMPTGS1XIAP
SCHEMBL42306 0.97 BCAT2 (0.43) BCAT2ALPIPKMPTGS1XIAP
SCHEMBL7459500 0.97 BCAT2 (0.43) BCAT2ALPIPKMPTGS1XIAP
SCHEMBL42307 0.97 BCAT2 (0.43) BCAT2ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL5706573 0.95 BCAT2 (0.42) BCAT2ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL8426381 0.95 BCAT2 (0.42) BCAT2ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL5706571 0.95 BCAT2 (0.42) BCAT2ALPIPKMPTGS1XIAP
Valine SCHEMBL7460247 0.87 SLC1A3 (0.41) BCAT2ALPIPKMPTGS1XIAP
Carbamic Acid SCHEMBL28108559 0.80 DPP4 (0.48) ALDH1A1
SCHEMBL7027775 0.79 EPHX1 (0.36) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873308-B1 O-CARBAMOYL-PHENYLALANINOL COMPOUNDS AND THEIR PHARMACEUTICALLY USEFUL SALTS SK CORP (KR) 2002-01-02 EP disclosed
EP-0873308-A1 O-CARBAMOYL-PHENYLALANINOL COMPOUNDS, THEIR PHARMACEUTICALLY USEFUL SALTS AND PROCESS FOR PREPARING THE SAME SK Corporation (KR) 1998-10-28 EP disclosed
US-5756817-A TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEMS YUKONG LIMITED (KR) 1998-05-26 US disclosed
WO-1998015526-A1 O-CARBAMOYL-PHENYLALANINOL COMPOUNDS, THEIR PHARMACEUTICALLY USEFUL SALTS AND PROCESS FOR PREPARING THE SAME SK CORPORATION (KR) 1998-04-16 WO disclosed