Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 8/20 | 0.54 |
| ▸ | HTR2B | P41595 | 8/20 | 0.54 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.54 |
| ▸ | PPIA | P62937 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7657697 | 0.99 | SMN1; SMN2 (0.57) | SMN1; SMN2HTR2CHTR2BPTK6PPIA | |
| Hydrochloric Acid SCHEMBL7658357 | 0.86 | HTR2C (0.59) | HTR2CHTR2BPTK6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7657613 | 0.85 | HTR2C (0.57) | HTR2CHTR2BTRPV1 | |
| SCHEMBL7447310 | 0.84 | HTR2C (0.67) | HTR2CHTR2BPTK6MEN1KMT2A | |
| SCHEMBL15923162 | 0.84 | PTK6 (0.67) | SMN1; SMN2PTK6CTSVCTSL | |
| SCHEMBL31197402 | 0.84 | PTK6 (0.67) | SMN1; SMN2PTK6CTSVCTSL | |
| Hydrochloric Acid SCHEMBL8808426 | 0.83 | PTK6 (0.65) | SMN1; SMN2PTK6CTSVCTSL | |
| SCHEMBL28390021 | 0.82 | MEN1 (0.71) | PPIAMEN1KMT2ANPC1POLB | |
| SCHEMBL7447576 | 0.82 | HTR2C (0.63) | SMN1; SMN2HTR2CHTR2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7665874 | 0.81 | HTR2C (0.58) | HTR2CHTR2BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003737-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999009024-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-02-25 | — | — | WO | disclosed |