SCHEMBL7456136

SCHEMBL7456136

CCCCCC[CH]Oc1ccc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.38
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
CYP2C19 P33261 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CNR2 P34972 4/20 0.33
CNR1 P21554 3/20 0.33
ESR1 P03372 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
KDM4E B2RXH2 2/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
APEX1 P27695 1/20 0.32
NR5A2 O00482 1/20 0.32
NR5A1 Q13285 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10908204 0.94 MAPT (0.35) GHSRTHRATHRBCYP2C19MAPT
SCHEMBL10907308 0.88 NPSR1 (0.37) CYP2C19MAPTMAPK1NPSR1KDM4E
SCHEMBL7454444 0.83 MAPK1 (0.45) GHSRMAPTMAPK1NPSR1CNR2
SCHEMBL9769414 0.82 CNR2 (0.36) MAPTMAPK1NPSR1CNR2CNR1
SCHEMBL9769416 0.82 CNR2 (0.46) CNR2CNR1
SCHEMBL986848 0.82 NPSR1 (0.39) CYP2C19MAPTMAPK1NPSR1KDM4E
SCHEMBL7456145 0.79 THRA (0.54) THRATHRBMAPTMAPK1NPSR1
SCHEMBL10810675 0.78 THRA (0.41) GHSRTHRATHRBCYP2C19MAPT
SCHEMBL5394859 0.77 MAPK1 (0.47) MAPTMAPK1NPSR1CNR2CNR1
SCHEMBL8987217 0.76 MAPK1 (0.37) CYP2C19MAPTMAPK1NPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020128488-A1 Azomethine compound and oily magenta ink FUJI PHOTO FILM CO., LTD. 2002-09-12 US disclosed
US-6383276-B1 INK JET PRINTING FUJI PHOTO FILM CO., LTD. (JP) 2002-05-07 US disclosed
EP-1035172-A2 Azomethine compound and oily magenta ink FUJI PHOTO FILM CO., LTD. (JP) 2000-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128488-A1 Azomethine compound and oily magenta ink IK, RB1, TYR GHSR 4036/4885THRA 4257/4885THRB 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.