Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | CCR3 | P51677 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463105 | 0.88 | MCHR1 (0.65) | MCHR1CCR3CCR5CCR1MEN1 | |
| Hydrochloric Acid SCHEMBL7466982 | 0.87 | MCHR1 (0.51) | MCHR1CCR3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7463703 | 0.87 | MCHR1 (0.64) | MCHR1CCR3CCR5MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7458660 | 0.86 | MCHR1 (0.51) | MCHR1CHRM2CHRM3CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7456215 | 0.86 | MCHR1 (0.50) | MCHR1CHRM2CHRM3CCR3CCR5 | |
| SCHEMBL7462119 | 0.86 | MCHR1 (0.50) | MCHR1CHRM2CHRM3CCR3CCR5 | |
| SCHEMBL7463245 | 0.85 | MCHR1 (0.53) | MCHR1CHRM2CHRM3BCHECCR3 | |
| Hydrochloric Acid SCHEMBL7466911 | 0.84 | MCHR1 (0.56) | MCHR1CHRM3CCR3CCR1OPRM1 | |
| Hydrochloric Acid SCHEMBL7466657 | 0.84 | MCHR1 (0.54) | MCHR1CCR3OPRM1 | |
| Hydrochloric Acid SCHEMBL7461507 | 0.84 | MCHR1 (0.58) | MCHR1BCHECCR3CCR5CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |