Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378188 | 1.00 | TNFRSF1A (0.51) | TNFRSF1AAKR1C2MEN1KMT2APOLB | |
| SCHEMBL7464347 | 0.92 | TNFRSF1A (0.48) | TNFRSF1AAKR1C2MEN1KMT2APOLB | |
| SCHEMBL7464120 | 0.92 | TNFRSF1A (0.48) | TNFRSF1AAKR1C2MEN1KMT2APOLB | |
| SCHEMBL7464113 | 0.92 | TNFRSF1A (0.48) | TNFRSF1AAKR1C2MEN1KMT2APOLB | |
| SCHEMBL7372138 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7379313 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7379318 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7381622 | 0.82 | ALDH1A1 (0.44) | MEN1KMT2AABCB1TUBB1KDM4E | |
| SCHEMBL7467391 | 0.82 | ALDH1A1 (0.44) | MEN1KMT2AABCB1TUBB1KDM4E | |
| SCHEMBL7467398 | 0.82 | ALDH1A1 (0.44) | MEN1KMT2AABCB1TUBB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889879-B1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6248743-B1 | ANTITHROMBOTIC AGENTS EFFECTIVE TO INHIBIT THE PRODUCTION OF TYPE 1 PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) | TANABE SEIYAKU CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |