Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746760 | 1.00 | ABCB1 (0.54) | ABCB1MAPTNPSR1PDPK1TTR | |
| SCHEMBL20858964 | 0.93 | ABCB1 (0.49) | ABCB1MAPTNPSR1PDPK1TTR | |
| SCHEMBL3706909 | 0.92 | ABCB1 (0.65) | ABCB1 | |
| SCHEMBL743627 | 0.92 | ABCB1 (0.65) | ABCB1 | |
| SCHEMBL7030048 | 0.91 | ABCB1 (0.53) | ABCB1MAPTNPSR1 | |
| SCHEMBL7028453 | 0.90 | ABCB1 (0.47) | ABCB1MAPTNPSR1PDPK1TTR | |
| SCHEMBL744489 | 0.90 | ABCB1 (0.56) | ABCB1MAPT | |
| SCHEMBL7030123 | 0.89 | ABCB1 (0.57) | ABCB1 | |
| SCHEMBL20858974 | 0.86 | ABCB1 (0.57) | ABCB1MAPTPDPK1TTRALOX5 | |
| SCHEMBL20858975 | 0.85 | ABCB1 (0.47) | ABCB1MAPTNPSR1PDPK1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429292-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR THE TREATMENT OF CANCER | Georgia State University Research Foundation, Inc. (US) | 2012-03-21 | — | — | EP | claimed |
| WO-2010129858-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR THE TREATMENT OF CANCER | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-11-11 | — | — | WO | claimed |
| EP-2429292-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR THE TREATMENT OF CANCER | Georgia State University Research Foundation, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010129858-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR THE TREATMENT OF CANCER | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-11-11 | — | — | WO | disclosed |