Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745732 | 1.00 | CCR2 (0.75) | CCR2KCNH2 | |
| SCHEMBL744134 | 0.90 | CCR2 (0.75) | CCR2KCNH2 | |
| SCHEMBL744135 | 0.90 | CCR2 (0.75) | CCR2KCNH2 | |
| SCHEMBL744136 | 0.90 | CCR2 (0.75) | CCR2KCNH2 | |
| SCHEMBL5233885 | 0.90 | CCR2 (0.74) | CCR2KCNH2 | |
| SCHEMBL744875 | 0.90 | CCR2 (0.76) | CCR2KCNH2 | |
| SCHEMBL746526 | 0.90 | CCR2 (0.71) | CCR2KCNH2 | |
| SCHEMBL746426 | 0.89 | CCR2 (0.80) | CCR2KCNH2 | |
| SCHEMBL747307 | 0.89 | CCR2 (0.82) | CCR2KCNH2 | |
| SCHEMBL745061 | 0.88 | CCR2 (0.78) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431357-A2 | 3-Aminopyrrolidine Derivatives as Modulators of Chemokine Receptors | Incyte Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-1565436-A4 | 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1565436-A2 | 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004050024-A2 | 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2004-06-17 | — | — | WO | disclosed |