Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FBP1 | P09467 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14641990 | 0.80 | KMT2A (0.50) | KMT2AMEN1ACHEALDH1A1FBP1 | |
| SCHEMBL822302 | 0.76 | KMT2A (0.59) | KMT2AMEN1ACHEALDH1A1FBP1 | |
| SCHEMBL29468572 | 0.76 | KMT2A (0.59) | KMT2AMEN1ACHEALDH1A1FBP1 | |
| SCHEMBL22818584 | 0.74 | ALDH1A1 (0.51) | KMT2AALDH1A1CA12CA1CA2 | |
| SCHEMBL12808 | 0.74 | KMT2A (0.57) | KMT2AMEN1ACHEALDH1A1FBP1 | |
| Hydrochloric Acid SCHEMBL11279258 | 0.74 | KMT2A (0.57) | KMT2AMEN1ACHEALDH1A1FBP1 | |
| SCHEMBL15607666 | 0.74 | KMT2A (0.57) | KMT2AMEN1ACHEALDH1A1MAPT | |
| SCHEMBL1721592 | 0.74 | GAA (0.54) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL330676 | 0.74 | KMT2A (0.57) | KMT2AMEN1ACHEALDH1A1FBP1 | |
| SCHEMBL29547938 | 0.73 | KMT2A (0.67) | KMT2AMEN1ALDH1A1FBP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162962-A4 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1162962-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6232503-B1 | MICROBIOCIDES | LONZA INC. | 2001-05-15 | — | — | US | disclosed |
| WO-2000056305-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2000-09-28 | — | — | WO | disclosed |