Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457839 | 1.00 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7457834 | 1.00 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4144592 | 0.87 | SLC6A3 (0.56) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4144590 | 0.87 | SLC6A3 (0.56) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7358586 | 0.86 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2996399 | 0.86 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7358592 | 0.86 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7353829 | 0.86 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2996400 | 0.86 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2996397 | 0.86 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756596-B1 | TROPANE-2-ALDOXIME DERIVATIVES AS NEUROTRANSMITTER REUPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2002-08-21 | — | — | EP | disclosed |