Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454537 | 1.00 | NAAA (0.43) | NAAAHTR2AASAH1KCNH2PRSS1 | |
| SCHEMBL11834538 | 1.00 | NAAA (0.43) | NAAAHTR2AASAH1KCNH2PRSS1 | |
| SCHEMBL6723008 | 1.00 | NAAA (0.43) | NAAAHTR2AASAH1KCNH2PRSS1 | |
| SCHEMBL7455004 | 1.00 | NAAA (0.43) | NAAAHTR2AASAH1KCNH2PRSS1 | |
| SCHEMBL7452348 | 1.00 | NAAA (0.43) | NAAAHTR2AASAH1KCNH2PRSS1 | |
| SCHEMBL6719347 | 1.00 | NAAA (0.43) | NAAAHTR2AASAH1KCNH2PRSS1 | |
| SCHEMBL7454063 | 1.00 | NAAA (0.43) | NAAAHTR2AASAH1KCNH2PRSS1 | |
| SCHEMBL6723122 | 0.98 | NAAA (0.41) | NAAAHTR2AASAH1KCNH2PRSS1 | |
| SCHEMBL143657 | 0.93 | POLB (0.45) | NAAAHTR2AALDH1A1OPRM1OPRD1 | |
| SCHEMBL28799952 | 0.85 | AOC3 (0.42) | HTR2APOLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015109451-A1 | SYNTHESIS OF COMPOUNDS CONTAINING 8-OXA-3-AZABICYCLO (3.2.1)OCTANE RING | RHODIA OPERATIONS (FR) | 2015-07-30 | — | — | WO | disclosed |
| EP-1167375-A1 | ERYTHROMYCIN DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-3975532-A | ANALGESIC | ICI UNITED STATES INC. (US) | 1976-08-17 | — | — | US | disclosed |
| US-3953596-A | 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals | ICI UNITED STATES INC. (US) | 1976-04-27 | — | — | US | disclosed |