Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.62 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.62 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725667 | 0.88 | CYSLTR1 (0.46) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7458449 | 0.86 | CYSLTR1 (0.62) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL5725146 | 0.85 | CYSLTR1 (0.67) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL5726112 | 0.83 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6089372 | 0.82 | CYSLTR1 (0.62) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6087968 | 0.80 | CYSLTR1 (0.56) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL6087603 | 0.80 | CYSLTR1 (0.64) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7469798 | 0.80 | CYSLTR1 (0.40) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7714863 | 0.80 | CYSLTR1 (0.66) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7459008 | 0.80 | CYSLTR1 (0.73) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |