Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469808 | 0.87 | CYSLTR1 (0.40) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL6090077 | 0.83 | CYSLTR1 (0.42) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6088342 | 0.82 | CYSLTR1 (0.35) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL7458445 | 0.80 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL5725667 | 0.75 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1PDE10ACCNB2 | |
| SCHEMBL7460389 | 0.73 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL6088777 | 0.72 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6089165 | 0.70 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2 | |
| SCHEMBL6087773 | 0.69 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6091468 | 0.68 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |