Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.83 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.83 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.83 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29998343 | 1.00 | ESR1 (0.83) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL23851086 | 0.91 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL5354173 | 0.91 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL5818558 | 0.91 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL639225 | 0.91 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL5354177 | 0.91 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL7723356 | 0.91 | ESR1 (1.00) | ESR1ESR2CYP19A1PTGS2PGR | |
| Phenol SCHEMBL7723405 | 0.90 | ESR1 (0.96) | ESR1ESR2CYP19A1PTGS2PGR | |
| Phenol SCHEMBL10796309 | 0.90 | ESR1 (0.96) | ESR1ESR2CYP19A1PTGS2PGR | |
| Phenol SCHEMBL10796314 | 0.90 | ESR1 (0.96) | ESR1ESR2CYP19A1PTGS2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235776-A1 | TRIPHENYLALKENE DERIVATIVES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | Hormos Medical Corporation (FI) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001036360-A1 | TRIPHENYLALKENE DERIVATIVES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | HORMOS MEDICAL CORPORATION (FI) | 2001-05-25 | — | — | WO | disclosed |