SCHEMBL7458744

SCHEMBL7458744

C[C@H]1OC(Sc2ccccc2)[C@H](O)[C@H]2OC(C)(C)O[C@H]21

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
LGALS3 P17931 3/20 0.33
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14962616 1.00 CYP3A4 (0.35) CYP3A4MAPK1LGALS3ALDH1A1MEN1
SCHEMBL7999756 1.00 CYP3A4 (0.35) CYP3A4MAPK1LGALS3ALDH1A1MEN1
SCHEMBL582240 1.00 CYP3A4 (0.35) CYP3A4MAPK1LGALS3ALDH1A1MEN1
SCHEMBL14968526 1.00 CYP3A4 (0.35) CYP3A4MAPK1LGALS3ALDH1A1MEN1
SCHEMBL12691080 0.90 CYP3A4 (0.34) CYP3A4MAPK1LGALS3ALDH1A1MEN1
SCHEMBL4279232 0.86 GSTP1 (0.32) LGALS3
SCHEMBL13657211 0.86 GSTP1 (0.32) LGALS3
SCHEMBL8015303 0.82 CA12 (0.42) LGALS3ALDH1A1
SCHEMBL12691651 0.81 CYP3A4 (0.33) CYP3A4MAPK1ALDH1A1
SCHEMBL5691368 0.78 FUCA1 (0.44) MAPK1LGALS3ALDH1A1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0910568-A4 SULFINYL HEXOSE DERIVATIVES USEFUL FOR GLYCOSYLATION UNIV PRINCETON (US) 2002-04-24 EP disclosed
EP-0910568-A1 SULFINYL HEXOSE DERIVATIVES USEFUL FOR GLYCOSYLATION PRINCETON UNIVERSITY (US) 1999-04-28 EP disclosed
WO-1997034906-A1 SULFINYL HEXOSE DERIVATIVES USEFUL FOR GLYCOSYLATION PRINCETON UNIVERSITY (US) 1997-09-25 WO disclosed