Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 3/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.31 |
| ▸ | GSTA2 | P09210 | 1/20 | 0.30 |
| ▸ | GSTM1 | P09488 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657211 | 1.00 | GSTP1 (0.32) | GSTP1LGALS3GSTA2GSTM1 | |
| SCHEMBL7458744 | 0.86 | CYP3A4 (0.35) | LGALS3 | |
| SCHEMBL14968526 | 0.86 | CYP3A4 (0.35) | LGALS3 | |
| SCHEMBL7999756 | 0.86 | CYP3A4 (0.35) | LGALS3 | |
| SCHEMBL582240 | 0.86 | CYP3A4 (0.35) | LGALS3 | |
| SCHEMBL14962616 | 0.86 | CYP3A4 (0.35) | LGALS3 | |
| SCHEMBL4274371 | 0.80 | GSTP1 (0.40) | GSTP1GSTA2GSTM1 | |
| SCHEMBL13657214 | 0.80 | GSTP1 (0.40) | GSTP1GSTA2GSTM1 | |
| SCHEMBL12691080 | 0.77 | CYP3A4 (0.34) | LGALS3 | |
| SCHEMBL5691368 | 0.74 | FUCA1 (0.44) | LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605241-B2 | Synthesis of inhibitors of p90Rsk | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-10-20 | — | — | US | disclosed |
| US-20080269144-A1 | Synthesis of Inhibitors of P90Rsk | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2008-10-30 | — | — | US | disclosed |
| EP-1845778-A2 | SYNTHESIS OF INHIBITORS OF P90RSK | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006086103-A2 | SYNTHESIS OF INHIBITORS OF P90RSK | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269144-A1 | Synthesis of Inhibitors of P90Rsk | RAF1, KSR1, STK10 | GSTP1 2365/4885LGALS3 4526/4885GSTA2 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.