⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20901 | 0.83 | — | — | |
| SCHEMBL6028419 | 0.79 | — | — | |
| SCHEMBL4153948 | 0.77 | — | — | |
| SCHEMBL8781985 | 0.77 | — | — | |
| SCHEMBL3026236 | 0.76 | — | — | |
| SCHEMBL1456280 | 0.75 | ABCG2 (0.30) | — | |
| SCHEMBL6199963 | 0.75 | — | — | |
| SCHEMBL26613482 | 0.75 | — | — | |
| SCHEMBL16402847 | 0.71 | — | — | |
| SCHEMBL467838 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284618-A1 | FURANOCHALCONES AS INHIBITORS OF CYP1A1, CYP1A2 AND CYP1B1 FOR CANCER CHEMOPREVENTION | COUNCIL SCIENT IND RES (IN) | 2021-09-16 | — | — | US | claimed |
| EP-3497097-A1 | FURANOCHALCONES AS INHIBITORS OF CYP1A1, CYP1A2 AND CYP1B1 FOR CANCER CHEMOPREVENTION | Council Of Scientific & Industrial Research (IN) | 2019-06-19 | — | — | EP | claimed |
| WO-2018029710-A1 | FURANOCHALCONES AS INHIBITORS OF CYP1A1, CYP1A2 AND CYP1B1 FOR CANCER CHEMOPREVENTION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-15 | — | — | WO | claimed |
| US-20130116230-A1 | 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2013-05-09 | — | — | US | claimed |
| US-8362003-B2 | 3-aminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2013-01-29 | — | — | US | claimed |
| EP-2431357-A2 | 3-Aminopyrrolidine Derivatives as Modulators of Chemokine Receptors | Incyte Corporation (US) | 2012-03-21 | — | — | EP | claimed |
| CN-101341129-B | Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor xia inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2011-12-14 | — | — | CN | claimed |
| US-8058285-B2 | Phosphodiesterase-4 (PDE-4) inhibitors; for treating bronchial asthma, COPD, rheumatoid arthritis (RA), osteoarthritis, cystic fibrosis, Guillain-Barresyndrome, Crohn's disease, ulcerative colitis, psoriasis, atopic dermatitis, allergic eczemas | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2011-11-15 | — | — | US | claimed |
| US-20110251168-A1 | 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION | 2011-10-13 | — | — | US | claimed |
| CN-101838269-A | 1,3,8-triaza-spiro[4.5]decane-4-ketone compounds and pharmaceutical application thereof | INST PHARM & TOXICOLOGY AMMS | 2010-09-22 | — | — | CN | claimed |
| WO-1998022494-A2 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | claimed |
| WO-1998017656-A1 | A FAMILY OF CANADENSOL TAXANES, THE SEMI-SYNTHETIC PREPARATION AND THERAPEUTIC USE THEREOF | INSTITUTE ARMAND-FRAPPIER (CA) | 1998-04-30 | — | — | WO | claimed |
| WO-1997045016-A1 | NOVEL N-ACYL SULPHONAMIDES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THEIR USE | HOECHST SCHERING AGREVO GMBH (DE) | 1997-12-04 | — | — | WO | claimed |
| WO-1997017071-A1 | STEREOSELECTIVE SYNTHESIS OF ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| US-4772534-A | PHOTORESISTS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-20 | — | — | US | claimed |
| EP-0060962-B1 | MICROBICIDAL TRIAZOLYL METHYL DIOXOLANES AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1985-08-07 | — | — | EP | claimed |
| EP-0010420-B1 | PYRIDYL-SUBSTITUTED THIAZOLIDINE AND 1,3-THIAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AGRICULTURAL COMPOSITIONS CONTAINING SAID DERIVATIVES AND METHODS FOR REGULATING PLANT GROWTH AND PROTECTING PLANTS FROM FUNGI | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | claimed |
| US-4429031-A | ISOPROPYLHYDROQUINONE DERIVATIVE TO CONTROL GRADATION | FUJI PHOTO FILM CO., LTD. (JP) | 1984-01-31 | — | — | US | claimed |
| US-4336260-A | Method and compositions using 1-aryl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid for treating depression | THE DOW CHEMICAL COMPANY (US) | 1982-06-22 | — | — | US | claimed |
| US-4118561-A | ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-10-03 | — | — | US | claimed |