SCHEMBL8781985

SCHEMBL8781985

[c]1ccc2c(c1)OC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1456280 0.83 ABCG2 (0.30)
SCHEMBL1239247 0.81 LMNA (0.39)
SCHEMBL3998995 0.80 CYP1A2 (0.35)
SCHEMBL1461403 0.79 MAOA (0.36)
SCHEMBL102103 0.77
SCHEMBL745905 0.77
SCHEMBL910334 0.74 CLK1 (0.33)
SCHEMBL16402847 0.74
SCHEMBL27032744 0.73 CA1 (0.31)
SCHEMBL5840401 0.73 MAOA (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109369584-B 2-aryl/alkyl-3- (substituted olefin) naphthofuran derivatives and synthetic method thereof 华东师范大学 2022-10-04 CN claimed
CN-105503490-B Process for preparing chiral gamma-secondary amino alcohol 上海交通大学 2020-07-03 CN claimed
CN-114560888-A Preparation method of alpha, beta-unsaturated phosphonamide compound 北京化工大学 2022-05-31 CN disclosed
CN-111995643-B Pentacyclic benzo-delta-phosphine lactam compound and preparation method thereof 北京化工大学 2022-05-17 CN disclosed
CN-113717228-A Beta-phosphinic lactam compound and preparation method thereof 北京化工大学 2021-11-30 CN disclosed
CN-111995643-A Pentacyclic benzo-phosphine lactam compound and preparation method thereof 北京化工大学 2020-11-27 CN disclosed
CN-106278932-B Cyclic alpha-dehydroaminoketone, chiral cyclic alpha-aminoketone and preparation method thereof 上海交通大学 2020-10-09 CN disclosed
CN-105503490-B Process for preparing chiral gamma-secondary amino alcohol 上海交通大学 2020-07-03 CN disclosed
EP-0167168-B2 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1997-07-02 EP disclosed
US-5190846-A Storage stability, high releasing speed, sharp image, contrast FUJI PHOTO FILM CO., LTD. (JP) 1993-03-02 US disclosed
US-5142029-A Redox system FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
US-5132201-A Silver halide photographic material with redox releaser FUJI PHOTO FILM CO., LTD. (JP) 1992-07-21 US disclosed
EP-0167168-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-11-15 EP disclosed
EP-0198438-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-18 EP disclosed
US-4770990-A Silver halide photographic light-sensitive material containing a compound capable of imagewise releasing a photographically useful group during development FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
EP-0198438-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-10-22 EP disclosed
EP-0167168-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1986-01-08 EP disclosed