Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SORD | Q00796 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746081 | 0.81 | KDM4E (0.46) | KDM4EMAPTALDH1A1HSD17B10CMA1 | |
| SCHEMBL28743259 | 0.79 | MAPT (0.43) | KDM4EMAPTALDH1A1HSD17B10CMA1 | |
| SCHEMBL9933881 | 0.79 | MAPT (0.50) | KDM4EMAPTALDH1A1HSD17B10CMA1 | |
| SCHEMBL1122156 | 0.75 | MAPT (0.50) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL19141271 | 0.75 | KDM4E (0.50) | KDM4EMAPTALDH1A1HSD17B10CMA1 | |
| SCHEMBL9670628 | 0.75 | MAPT (0.50) | KDM4EMAPTALDH1A1HSD17B10CMA1 | |
| SCHEMBL38661082 | 0.75 | KDM4E (0.55) | KDM4EMAPTALDH1A1HSD17B10CMA1 | |
| SCHEMBL8371416 | 0.75 | MAPT (0.50) | KDM4EMAPTALDH1A1HSD17B10CMA1 | |
| SCHEMBL8906440 | 0.75 | KDM4E (0.50) | KDM4EMAPTALDH1A1HSD17B10CMA1 | |
| SCHEMBL11594753 | 0.74 | MAPT (0.46) | KDM4EMAPTALDH1A1HSD17B10CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1999014216-A1 | SUBSTITUTED 3(-1,2-BENZISOTHIAZOL OR ISOXAZOL-5 YL)-SUBSTITUTED PYRIMIDINE AS HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |