SCHEMBL1122156

SCHEMBL1122156

O=Cc1nsc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 2/20 0.50
HSD17B10 Q99714 1/20 0.50
EPAS1 Q99814 9/20 0.47
CYP2A6 P11509 1/20 0.42
EPHX2 P34913 1/20 0.39
DDAH1 O94760 1/20 0.36
LMNA P02545 1/20 0.36
CASP3 P42574 1/20 0.36
HTT P42858 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
MMP13 P45452 1/20 0.36
GPR3 P46089 1/20 0.36
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28833444 0.98 MAPT (0.48) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL7457542 0.81 MAPT (0.44) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL7457546 0.81 MAPT (0.44) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL3056272 0.79 KDM4E (0.50) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL7459121 0.75 KDM4E (0.46) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL7461568 0.74 HCAR2 (0.44) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL7461572 0.74 HCAR2 (0.44) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL7468486 0.73 MAPT (0.44) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL7468484 0.73 MAPT (0.44) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL28704624 0.73 ALDH1A1 (0.38) MAPTKDM4EALDH1A1HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4323 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118299111-A Flexible medical cable for minimally invasive radio frequency ablation treatment and preparation method thereof 立则线缆(江苏)有限公司 2024-07-05 CN claimed
CN-116875073-B Wear-resistant composite plastic-wood material and preparation method thereof 美新工程材料(深圳)有限公司 2024-07-02 CN claimed
CN-118063402-A Synthesis process of saccharin 上海交通大学 2024-05-24 CN claimed
CN-115340626-B Sterilization and antifouling resin grafted with phenolic isothiazolinone acrylate monomer and preparation method thereof 广东省漆色彩新型材料有限公司 2024-05-24 CN claimed
CN-117888390-B Super-hydrophobic coating on inner surface of corrugated paper and preparation method thereof 盐城富邦包装有限公司 2024-05-14 CN claimed
CN-117701116-B Ultraviolet-resistant decorative joint mixture and preparation process thereof 广州市钢玉建筑材料有限公司 2024-05-14 CN claimed
CN-117987220-A Three-cavity coated laundry gel bead with disinfection, sterilization and decontamination functions 上海银燕消毒剂厂 2024-05-07 CN claimed
CN-117888390-A Super-hydrophobic coating on inner surface of corrugated paper and preparation method thereof 盐城富邦包装有限公司 2024-04-16 CN claimed
CN-117757556-A Woodworking screw head forming liquid and preparation method thereof 嘉兴顺诚精细化工有限公司 2024-03-26 CN claimed
CN-117701116-A Ultraviolet-resistant decorative joint mixture and preparation process thereof 广州市钢玉建筑材料有限公司 2024-03-15 CN claimed
CN-1179152-A Process for preparation of 1, 2 -benzisothiazolin -3 -ones compounds ZENECA LTD (GB) 1998-04-15 CN claimed
CN-1143452-A Liquid formulations of 1,2-benzisothiazolin-3-one HULS AMERICA INC (US) 1997-02-26 CN claimed
CN-1140392-A Pesticidal micronutrient composition contg. zinc oxide ISK BIOTECH CORP (US) 1997-01-15 CN claimed
CN-1119645-A Method for producing 1,2-benzisothiazol-3-ones 21678/01 SUMITOMO SEIKA CHEMICALS (JP) 1996-04-03 CN claimed
CN-1116221-A Aqueous ball point ink composition SAKURA COLOR PROD CORP (JP) 1996-02-07 CN claimed
CN-1107837-A Process for producing alkylsulfinylbenzamides and 1, 2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1995-09-06 CN claimed
CN-1081564-A Pesticide composition of 3-hydroxy-5-methyl isoxazole and use method SANKYO CO (JP) 1994-02-09 CN claimed
CN-1019468-B ANTI-INSECTIVAL AND ANTIFUNGAL BAG FOR CEREALS MARUSHO KASEI KK (JP) 1992-12-16 CN claimed
CN-1035471-A The insect protected and the mould proof bag that are used for cereal MARUSHO KASEI KK (JP) 1989-09-13 CN claimed
CN-86104730-A ISOTHIAZOLONE AQUEOUS SOLUTION 1987-01-14 CN claimed