Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7750263 | 0.98 | ELOVL6 (0.48) | ELOVL6OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL18151913 | 0.82 | ELOVL6 (0.52) | ELOVL6L3MBTL3L3MBTL1ACHEHTR3E | |
| SCHEMBL21162194 | 0.80 | ELOVL6 (0.53) | ELOVL6L3MBTL3L3MBTL1CHRM3ACHE | |
| SCHEMBL20362472 | 0.77 | BCL2 (0.43) | OPRM1OPRD1OPRK1KCNH2CHRM3 | |
| SCHEMBL31716435 | 0.76 | PLG (0.42) | OPRM1OPRD1OPRK1KCNH2CHRM3 | |
| SCHEMBL18686529 | 0.76 | PLG (0.42) | OPRM1OPRD1OPRK1KCNH2CHRM3 | |
| SCHEMBL18686531 | 0.76 | PLG (0.42) | OPRM1OPRD1OPRK1KCNH2CHRM3 | |
| SCHEMBL5357723 | 0.76 | HTR2C (0.51) | ALDH1A1 | |
| SCHEMBL5357729 | 0.76 | HTR2C (0.51) | ALDH1A1 | |
| SCHEMBL19013662 | 0.75 | KDM4E (0.45) | ELOVL6OPRM1OPRD1L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021442-B1 | 8-AZABICYCLO 3.2.1] OCTANE-3-METHANAMINE DERIVATIVES AS LIGANDS OF D2 AND D3 DOPAMINE AND 5HT1A AND 5HT2 SEROTONIN RECEPTORS | SANOFI SYNTHELABO (FR) | 2002-01-30 | — | — | EP | disclosed |
| US-6221879-B1 | 8-azabicyclo[3.2.1] octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors | SANOFI-SYNTHELABO (FR) | 2001-04-24 | — | — | US | disclosed |