Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294049 | 0.92 | POLB (0.58) | POLBGAADPP4SMN1; SMN2HTT | |
| SCHEMBL5499784 | 0.77 | POLB (0.66) | POLBGAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL1538426 | 0.77 | POLB (0.66) | POLBGAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7951946 | 0.77 | POLB (0.66) | POLBGAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL25192028 | 0.77 | POLB (0.45) | POLBGAADPP4SMN1; SMN2HTT | |
| SCHEMBL26660473 | 0.77 | KMT2A (0.46) | POLBSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL11627254 | 0.77 | BRD4 (0.49) | POLBDPP4L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL15084846 | 0.74 | POLB (0.62) | POLBGAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL8293964 | 0.74 | POLB (0.67) | POLBGAASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL2772183 | 0.74 | POLB (0.62) | POLBGAASMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180513-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-20 | — | — | EP | disclosed |