Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 13/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 13/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7454448 | 0.95 | F2 (0.43) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7458550 | 0.91 | F2 (0.41) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7360778 | 0.85 | SMN1; SMN2 (0.41) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7364865 | 0.79 | SMN1; SMN2 (0.39) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7459282 | 0.77 | F2 (0.62) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7368633 | 0.77 | NR1H4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL7463042 | 0.77 | F2 (0.38) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7454841 | 0.76 | F2 (0.60) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7368094 | 0.74 | CA1 (0.38) | ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7458548 | 0.74 | F2 (0.58) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |