Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364865 | 0.94 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1MAPTGMNNLMNA | |
| Hydrochloric Acid SCHEMBL7463042 | 0.86 | F2 (0.38) | ALDH1A1MAPTLMNACA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7459292 | 0.85 | F2 (0.44) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7368094 | 0.81 | CA1 (0.38) | ALDH1A1CA1CA2HDAC3HDAC4 | |
| Trifluoroacetic Acid SCHEMBL7454448 | 0.80 | F2 (0.43) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7458550 | 0.79 | F2 (0.41) | ALDH1A1MAPTLMNAFFAR1FFAR4 | |
| SCHEMBL7363933 | 0.78 | F2 (0.36) | SMN1; SMN2ALDH1A1MAPTLMNACA1 | |
| SCHEMBL7368633 | 0.76 | NR1H4 (0.41) | — | |
| SCHEMBL7360137 | 0.76 | CA1 (0.36) | SMN1; SMN2ALDH1A1CA1CA2HDAC3 | |
| SCHEMBL7361146 | 0.75 | F2 (0.40) | SMN1; SMN2ALDH1A1MAPTGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |