Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.54 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | CTSG | P08311 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406322 | 1.00 | ELANE (0.54) | ELANEF2CTSG | |
| SCHEMBL7459291 | 1.00 | ELANE (0.54) | ELANEF2CTSG | |
| SCHEMBL7404559 | 0.89 | PREP (0.58) | — | |
| SCHEMBL7407388 | 0.88 | ELANE (0.43) | ELANEF2CTSG | |
| SCHEMBL7498102 | 0.86 | ELANE (0.50) | ELANEF2CTSG | |
| SCHEMBL6618550 | 0.86 | ELANE (0.54) | ELANEF2CTSG | |
| SCHEMBL6624127 | 0.86 | ELANE (0.50) | ELANEF2CTSG | |
| SCHEMBL6618027 | 0.86 | ELANE (0.50) | ELANEF2CTSG | |
| SCHEMBL6621333 | 0.85 | ELANE (0.49) | ELANEF2CTSG | |
| SCHEMBL7989953 | 0.85 | ELANE (0.49) | ELANEF2CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973775-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043975-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |