Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | ARG1 | P05089 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7459347 | 0.99 | HDAC8 (0.58) | HDAC8POLBOPRD1DPP4ALPI | |
| Hydrochloric Acid SCHEMBL7459337 | 0.99 | HDAC8 (0.58) | HDAC8POLBOPRD1DPP4ALPI | |
| SCHEMBL29910014 | 0.88 | ALDH1A1 (0.50) | HDAC8POLBDPP4FAPDPP8 | |
| SCHEMBL28499545 | 0.88 | ALDH1A1 (0.50) | HDAC8POLBDPP4FAPDPP8 | |
| SCHEMBL3142017 | 0.80 | HDAC8 (0.66) | HDAC8POLBOPRD1DPP4ALPI | |
| SCHEMBL27545467 | 0.80 | HDAC8 (0.66) | HDAC8POLBOPRD1DPP4ALPI | |
| SCHEMBL7835478 | 0.80 | HDAC8 (0.66) | HDAC8POLBOPRD1DPP4ALPI | |
| SCHEMBL6052908 | 0.80 | HDAC8 (0.66) | HDAC8POLBOPRD1DPP4ALPI | |
| SCHEMBL6052777 | 0.80 | HDAC8 (0.66) | HDAC8POLBOPRD1DPP4ALPI | |
| SCHEMBL2376034 | 0.80 | HDAC8 (0.61) | HDAC8POLBOPRD1DPP4ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020031816-A1 | METHOD OF INHIBITION OF HUMAN GLYCOGEN PHOSPHORYLASE | PFIZER PRODUCTS INC. | 2002-03-14 | — | — | US | disclosed |
| EP-0978279-A1 | Inhibitors of human glycogen phosphorylase | Pfizer Products Inc. (US) | 2000-02-09 | — | — | EP | disclosed |