Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459590 | 1.00 | TDP1 (0.54) | TDP1LMNAGSK3BF3THRB | |
| SCHEMBL7464390 | 0.91 | TDP1 (0.57) | TDP1LMNAGSK3BF3THRB | |
| SCHEMBL7464384 | 0.91 | TDP1 (0.57) | TDP1LMNAGSK3BF3THRB | |
| SCHEMBL11880728 | 0.86 | KMT2A (0.50) | TDP1LMNAATMMEN1KMT2A | |
| SCHEMBL11880732 | 0.86 | KMT2A (0.50) | TDP1LMNAATMMEN1KMT2A | |
| SCHEMBL10079591 | 0.83 | LMNA (0.52) | TDP1LMNAGSK3BF3THRB | |
| SCHEMBL8157084 | 0.81 | TDP1 (0.64) | TDP1LMNAGSK3BF3THRB | |
| SCHEMBL7454597 | 0.81 | TSHR (0.43) | TDP1LMNAGSK3BF3THRB | |
| SCHEMBL7454599 | 0.81 | TSHR (0.43) | TDP1LMNAGSK3BF3THRB | |
| SCHEMBL19244435 | 0.79 | TDP1 (0.60) | TDP1LMNAGSK3BF3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198220-A1 | SUNBLOCKING POLYMERS AND THEIR NOVEL FORMULATIONS | BIOPHYSICA, INC. (US) | 2002-04-24 | — | — | EP | claimed |
| WO-2001008647-A1 | SUNBLOCKING POLYMERS AND THEIR NOVEL FORMULATIONS | BIOPHYSICA, INC. (US) | 2001-02-08 | — | — | WO | claimed |
| US-6123928-A | Sunblocking polymers and their novel formulations | BIOPHYSICA, INC. (US) | 2000-09-26 | — | — | US | claimed |