Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464893 | 0.88 | NR4A2 (0.47) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7468079 | 0.86 | FGFR2 (0.47) | NR4A2SMN1; SMN2KDM4EALDH1A1FGFR2 | |
| SCHEMBL7467027 | 0.86 | NR4A2 (0.45) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7468223 | 0.85 | NR4A2 (0.47) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7466493 | 0.85 | NR4A2 (0.44) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL6589147 | 0.84 | NR4A2 (0.56) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7531657 | 0.84 | NR4A2 (0.59) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7463232 | 0.82 | SMN1; SMN2 (0.42) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7461220 | 0.82 | NR4A2 (0.47) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7461771 | 0.82 | NR4A2 (0.44) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |