Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.44 |
| ▸ | NT5E | P21589 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 3/20 | 0.43 |
| ▸ | PGK2 | P07205 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223843 | 1.00 | ADORA2A (0.44) | ADORA2AADORA3NT5EACHEPGK1 | |
| SCHEMBL7231338 | 0.96 | PGK1 (0.48) | ADORA2AADORA3NT5EPGK1PGK2 | |
| SCHEMBL7223844 | 0.95 | NT5E (0.44) | ADORA2AADORA3NT5EACHEPGK1 | |
| SCHEMBL7224964 | 0.93 | PGK1 (0.45) | ADORA2AADORA3NT5EACHEPGK1 | |
| Formic Acid SCHEMBL7223839 | 0.92 | PGK1 (0.48) | ADORA2AADORA3NT5EPGK1PGK2 | |
| SCHEMBL7231332 | 0.91 | PGK1 (0.49) | ADORA2AADORA3NT5EPGK1PGK2 | |
| SCHEMBL7229729 | 0.91 | ADORA2A (0.48) | ADORA2AADORA3PGK1PGK2ADORA2B | |
| SCHEMBL5086139 | 0.91 | PGK1 (0.51) | ADORA2AADORA3NT5EPGK1PGK2 | |
| SCHEMBL7226421 | 0.90 | ADORA2A (0.41) | ADORA2AADORA3PGK1PGK2ADORA2B | |
| SCHEMBL7230061 | 0.89 | ADORA2A (0.46) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | disclosed |