Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 14/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088850 | 1.00 | ADORA3 (0.52) | ADORA3ADORA2AADORA1ADORA2BCDK1 | |
| Formic Acid SCHEMBL7231390 | 0.97 | ADORA2A (0.49) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7459932 | 0.91 | ADORA3 (0.64) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7231395 | 0.91 | ADORA3 (0.43) | ADORA3ADORA2AADORA1ADORA2BCDK1 | |
| SCHEMBL7231392 | 0.91 | ADORA3 (0.43) | ADORA3ADORA2AADORA1ADORA2BCDK1 | |
| SCHEMBL2289136 | 0.89 | ADORA3 (0.68) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5600260 | 0.89 | ADORA3 (0.68) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL13296874 | 0.89 | ADORA3 (0.68) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL14538873 | 0.89 | ADORA3 (0.68) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL13296838 | 0.89 | ADORA3 (0.68) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | claimed |
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | claimed |