Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453942 | 0.94 | GAA (0.53) | GAATSHRSMN1; SMN2CDK1TP53 | |
| SCHEMBL7455445 | 0.92 | ALOX15 (0.43) | GAATSHRSMN1; SMN2ALOX15TP53 | |
| SCHEMBL7454655 | 0.91 | GAA (0.45) | GAATSHRSMN1; SMN2ALOX15CDK1 | |
| SCHEMBL7464037 | 0.91 | GAA (0.47) | GAATSHRSMN1; SMN2CDK1TP53 | |
| SCHEMBL7452294 | 0.87 | GAA (0.47) | GAATSHRSMN1; SMN2ALOX15CDK1 | |
| SCHEMBL9264502 | 0.87 | GAA (0.45) | GAATSHRSMN1; SMN2ALOX15CDK1 | |
| SCHEMBL9127057 | 0.86 | TSHR (0.50) | GAATSHRSMN1; SMN2CDK1TP53 | |
| SCHEMBL9262034 | 0.85 | GAA (0.45) | GAATSHRSMN1; SMN2ALOX15CDK1 | |
| SCHEMBL9271440 | 0.85 | GAA (0.49) | GAATSHRSMN1; SMN2ALOX15CDK1 | |
| SCHEMBL7455377 | 0.85 | GAA (0.50) | GAASMN1; SMN2CDK1TP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491893-B1 | ADMINISTERING COLONY STIMULATING FACTORS AND RADIONUCLIDE LABELS, THEN DETECTING USING TOMOGRAPHY OR MAGNETIC RESONANCE IMAGING | BIOSTREAM, INC. | 2002-12-10 | — | — | US | claimed |
| EP-0639190-B1 | PYRIDINE SULFONYL UREA DERIVATIVES | LG CHEM INVESTMENT LTD (KR) | 2002-01-09 | — | — | EP | claimed |
| US-5461026-A | Pyridine sulfonyl urea derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-10-24 | — | — | US | claimed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | claimed |
| EP-0639190-B1 | PYRIDINE SULFONYL UREA DERIVATIVES | LG CHEM INVESTMENT LTD (KR) | 2002-01-09 | — | — | EP | disclosed |
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | disclosed |