Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461938 | 0.92 | PPARG (0.36) | PPARG | |
| SCHEMBL8096316 | 0.88 | PPARG (0.40) | PPARGPTGDR2 | |
| SCHEMBL7462585 | 0.88 | PPARG (0.36) | PPARG | |
| SCHEMBL7467969 | 0.87 | PPARG (0.36) | PPARG | |
| SCHEMBL7458857 | 0.86 | BRD9 (0.36) | — | |
| SCHEMBL7465900 | 0.86 | PTGDR2 (0.39) | PPARGPTGDR2 | |
| SCHEMBL7460207 | 0.86 | ALDH1A1 (0.39) | PPARG | |
| SCHEMBL7457391 | 0.85 | PPARG (0.33) | PPARGPTGDR2ABCB11 | |
| SCHEMBL7452375 | 0.85 | PPARG (0.33) | PPARGPTGDR2ABCB11 | |
| SCHEMBL7458109 | 0.84 | HSP90AA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | claimed |
| US-6156700-A | 3-(1,2-Benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione herbicidal agents | AMERICAN CYANMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |