Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 4/20 | 0.71 |
| ▸ | HTR1D | P28221 | 3/20 | 0.71 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8618425 | 0.99 | HTR1B (0.70) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL1388869 | 0.87 | HTR1B (0.72) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| Oxalic Acid SCHEMBL7544492 | 0.85 | HTR1B (0.82) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL9333462 | 0.84 | HTR1B (0.93) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL7460912 | 0.81 | HTR1B (0.68) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL8527482 | 0.79 | HTR1B (0.69) | HTR1BHTR1DKDRHTR6NR2E1 | |
| SCHEMBL9305716 | 0.77 | BRD4 (0.56) | BRD4PDE3BPDE3AP2RY12 | |
| Hydrochloric Acid SCHEMBL9305103 | 0.77 | BRD4 (0.55) | BRD4PDE3BPDE3AP2RY12 | |
| SCHEMBL9303733 | 0.77 | BRD4 (0.55) | HTR1BHTR1DBRD4PDE3BPDE3A | |
| Oxalic Acid SCHEMBL7543521 | 0.76 | HTR1B (0.65) | HTR1BHTR1DKDRHTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782568-B1 | AROMATIC ETHERS DERIVED FROM INDOLS SUCH AS 5HT1-LIKE LIGANDS | PF MEDICAMENT (FR) | 2002-04-24 | — | — | EP | claimed |