Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 6/20 | 0.68 |
| ▸ | HTR1D | P28221 | 4/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7544492 | 0.87 | HTR1B (0.82) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL9333462 | 0.84 | HTR1B (0.93) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL1388869 | 0.83 | HTR1B (0.72) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL7460636 | 0.81 | HTR1B (0.71) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| Hydrochloric Acid SCHEMBL8618425 | 0.80 | HTR1B (0.70) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL7657783 | 0.75 | EGFR (0.67) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL6527024 | 0.75 | HTR1B (1.00) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| Hydrochloric Acid SCHEMBL7540641 | 0.74 | HTR1B (0.97) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL11844497 | 0.74 | HTR1B (0.53) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| Oxalic Acid SCHEMBL7540449 | 0.72 | HTR1B (0.66) | HTR1BHTR1DEGFRIGF1RFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782568-B1 | AROMATIC ETHERS DERIVED FROM INDOLS SUCH AS 5HT1-LIKE LIGANDS | PF MEDICAMENT (FR) | 2002-04-24 | — | — | EP | claimed |