Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.70 |
| ▸ | HTR1B | P28222 | 16/20 | 0.70 |
| ▸ | HTR1D | P28221 | 16/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8619243 | 0.99 | MAPT (0.69) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| SCHEMBL7456106 | 0.99 | HTR1A (0.71) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8615488 | 0.98 | MAPT (0.71) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| SCHEMBL7458272 | 0.97 | HTR1A (0.68) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8658704 | 0.96 | MAPT (0.67) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| SCHEMBL7461238 | 0.86 | HTR1A (0.67) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| SCHEMBL7460862 | 0.86 | MAPT (0.68) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| SCHEMBL1388943 | 0.85 | HTR1A (0.77) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| SCHEMBL7461622 | 0.85 | HTR1A (0.69) | HTR1AHTR1BHTR1DMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8614669 | 0.85 | HTR1A (0.66) | HTR1AHTR1BHTR1DMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782568-B1 | AROMATIC ETHERS DERIVED FROM INDOLS SUCH AS 5HT1-LIKE LIGANDS | PF MEDICAMENT (FR) | 2002-04-24 | — | — | EP | claimed |