Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.51 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810234 | 1.00 | FOLH1 (0.61) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL7461950 | 1.00 | FOLH1 (0.61) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL6810241 | 1.00 | FOLH1 (0.61) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL29814780 | 0.98 | FOLH1 (0.59) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL27611010 | 0.95 | FOLH1 (0.58) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL27611015 | 0.95 | FOLH1 (0.58) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL16770243 | 0.95 | FOLH1 (0.58) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL6810621 | 0.94 | FOLH1 (0.55) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL7461972 | 0.94 | FOLH1 (0.55) | FOLH1PTGS1GSTK1NAALAD2RIMKLA | |
| SCHEMBL30198445 | 0.94 | FOLH1 (0.55) | FOLH1PTGS1GSTK1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179055-A1 | NOVEL PHYTOCHELATIN SYNTHASES AND USES THEREFOR | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000071695-A1 | NOVEL PHYTOCHELATIN SYNTHASES AND USES THEREFOR | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-11-30 | — | — | WO | claimed |