SCHEMBL7462397

SCHEMBL7462397

Cn1c(C(F)(F)F)cc(=O)n(-c2cc3c(OC(=O)NS(=O)(=O)Cc4ccccc4)nsc3cc2F)c1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MET P08581 1/20 0.32
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7459240 0.88 PTPN1 (0.31)
SCHEMBL7461509 0.88 PTPN1 (0.34) METHTR7
SCHEMBL7457505 0.83
SCHEMBL7469221 0.81 KMT2A (0.33)
SCHEMBL7467058 0.79
SCHEMBL7462662 0.76
SCHEMBL7458623 0.76 PTPN1 (0.35) HTR7
SCHEMBL7556992 0.75 NPC1 (0.30)
SCHEMBL7455515 0.75
SCHEMBL7464232 0.74 SCN5A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002544197-A 2002-12-24 JP claimed
EP-0908457-B1 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents BASF AG (DE) 2002-11-13 EP claimed
EP-1177177-A1 SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 2002-02-06 EP claimed
WO-2000068202-A1 SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 2000-11-16 WO claimed