SCHEMBL7469221

SCHEMBL7469221

Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(OC(=O)NS(=O)(=O)Cc4cccc(Cl)c4)c3c2)c1=O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
PLA2G1B P04054 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
LIPG Q9Y5X9 1/20 0.30
LMNA P02545 1/20 0.30
S100A9 P06702 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7459240 0.92 PTPN1 (0.31)
SCHEMBL7458597 0.88 LIPG (0.33) KMT2AMEN1MAPTPLA2G1BL3MBTL1
SCHEMBL7467058 0.88
SCHEMBL7462662 0.84
SCHEMBL7454714 0.82
SCHEMBL7464232 0.82 SCN5A (0.30)
SCHEMBL7464828 0.82
SCHEMBL7458284 0.81
SCHEMBL7462397 0.81 MET (0.32)
SCHEMBL7556992 0.80 NPC1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908457-B1 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents BASF AG (DE) 2002-11-13 EP claimed