Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461228 | 0.92 | ITGB3 (0.42) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7457527 | 0.91 | ADORA2A (0.43) | ADORA2AITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7462112 | 0.89 | ADORA2A (0.54) | ADORA2AITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL27505326 | 0.83 | ADORA2A (0.43) | ADORA2ACACNA1B | |
| SCHEMBL7457387 | 0.83 | ADORA2A (0.43) | ADORA2ACACNA1B | |
| SCHEMBL7466875 | 0.82 | ITGB3 (0.42) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7460203 | 0.82 | ITGB3 (0.43) | ADORA2AITGB3ITGA2BCACNA1BF10 | |
| SCHEMBL7229073 | 0.79 | GRM2 (0.45) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7463401 | 0.79 | ITGB3 (0.45) | ADORA2AITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7462123 | 0.79 | ADORA2A (0.48) | ADORA2AITGB3PRSS1PRSS2ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697408-B1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 2002-01-23 | — | — | EP | disclosed |
| EP-0697408-A1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1996-02-21 | — | — | EP | disclosed |