Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGAV | P06756 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA5A | P35218 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465932 | 1.00 | F10 (0.48) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7455662 | 0.93 | ITGB3 (0.52) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7455657 | 0.93 | ITGB3 (0.52) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7456479 | 0.92 | F10 (0.47) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7455523 | 0.91 | ITGB3 (0.51) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7455533 | 0.91 | ITGB3 (0.51) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7457575 | 0.90 | F10 (0.47) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7464600 | 0.83 | ITGB3 (0.48) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7456957 | 0.82 | ITGB3 (0.47) | F10ITGB3ITGAVALDH1A1L3MBTL1 | |
| SCHEMBL7698171 | 0.82 | ITGB3 (0.53) | F10ITGB3ITGAVALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907637-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998000395-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 1998-01-08 | — | — | WO | disclosed |