Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466396 | 0.89 | CYP2D6 (0.43) | IDO1TDO2MEN1KMT2AMAPK1 | |
| SCHEMBL7466298 | 0.85 | IDO1 (0.37) | IDO1TDO2MEN1KMT2AMAPK1 | |
| SCHEMBL7461466 | 0.84 | PBRM1 (0.47) | ALDH1A1L3MBTL1PBRM1SRD5A2CA4 | |
| SCHEMBL7466782 | 0.83 | SRD5A2 (0.45) | IDO1TDO2PBRM1TSHRSLC6A4 | |
| SCHEMBL7461173 | 0.81 | IDO1 (0.50) | IDO1TDO2MEN1KMT2AALDH1A1 | |
| SCHEMBL7461086 | 0.80 | CASR (0.42) | L3MBTL1PBRM1SRD5A2 | |
| SCHEMBL7470957 | 0.78 | IDO1 (0.43) | IDO1TDO2OPRM1OPRD1SLC6A2 | |
| SCHEMBL7455793 | 0.78 | SRD5A2 (0.39) | IDO1TDO2KMT2AALDH1A1HTT | |
| SCHEMBL7460080 | 0.75 | IDO1 (0.49) | IDO1TDO2MEN1KMT2AOPRM1 | |
| SCHEMBL7456441 | 0.74 | IDO1 (0.54) | IDO1TDO2CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |