Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | TDO2 | P48775 | 5/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461173 | 0.82 | IDO1 (0.50) | IDO1TDO2CNR2SRD5A2ADRA2A | |
| SCHEMBL7466782 | 0.81 | SRD5A2 (0.45) | IDO1TDO2SLC6A4SRD5A2ADRA2A | |
| SCHEMBL7466731 | 0.81 | SLC6A4 (0.45) | IDO1TDO2ACP3OPRM1OPRK1 | |
| SCHEMBL7463226 | 0.78 | IDO1 (0.51) | IDO1TDO2OPRM1OPRD1SLC6A2 | |
| SCHEMBL7466690 | 0.77 | IDO1 (0.55) | IDO1TDO2ACP3SLC6A2SLC6A4 | |
| SCHEMBL7455793 | 0.76 | SRD5A2 (0.39) | IDO1TDO2SLC6A4SRD5A2PPARG | |
| SCHEMBL7464863 | 0.75 | IDO1 (0.45) | IDO1TDO2ACP3CNR2OPRM1 | |
| SCHEMBL11343236 | 0.74 | IDO1 (0.55) | IDO1TDO2ACP3CNR2OPRM1 | |
| SCHEMBL7466396 | 0.74 | CYP2D6 (0.43) | IDO1TDO2ADRA2A | |
| SCHEMBL6239957 | 0.73 | CNR2 (0.51) | IDO1TDO2ACP3CNR2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |