Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.80 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 9/20 | 0.41 |
| ▸ | CCR1 | P32246 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7465677 | 0.99 | MCHR1 (0.79) | MCHR1CHRM4CCR3CCR1ALDH1A1 | |
| SCHEMBL7463098 | 0.89 | MCHR1 (1.00) | MCHR1CCR3CCR1ALDH1A1PREP | |
| SCHEMBL7459747 | 0.89 | MCHR1 (0.78) | MCHR1CHRM4CCR3CCR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7463694 | 0.88 | MCHR1 (0.98) | MCHR1CCR3CCR1ALDH1A1PREP | |
| Hydrochloric Acid SCHEMBL7462015 | 0.88 | MCHR1 (0.77) | MCHR1CHRM4CCR3CCR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7461498 | 0.88 | MCHR1 (0.87) | MCHR1CHRM4CCR3CCR1ALDH1A1 | |
| SCHEMBL7463853 | 0.88 | MCHR1 (0.61) | MCHR1CHRM4CCR3CCR1DRD4 | |
| Hydrochloric Acid SCHEMBL7455700 | 0.86 | MCHR1 (0.71) | MCHR1CCR3CCR1ALDH1A1TPSAB1 | |
| SCHEMBL7458837 | 0.86 | MCHR1 (0.85) | MCHR1CHRM4CCR3CCR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7465351 | 0.86 | MCHR1 (0.83) | MCHR1CHRM4CCR3CCR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |