Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.78 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 4/20 | 0.40 |
| ▸ | CCR1 | P32246 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7462015 | 0.99 | MCHR1 (0.77) | MCHR1CACNA1GKCNH2CHRM4MEN1 | |
| SCHEMBL7463233 | 0.89 | MCHR1 (0.80) | MCHR1CHRM4DRD4CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7465677 | 0.88 | MCHR1 (0.79) | MCHR1CHRM4DRD4CCR3CCR1 | |
| SCHEMBL7463098 | 0.88 | MCHR1 (1.00) | MCHR1MEN1KMT2ACCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7463694 | 0.87 | MCHR1 (0.98) | MCHR1MEN1KMT2ACCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7466901 | 0.87 | MCHR1 (0.85) | MCHR1CHRM4CCR3CCR1ALDH1A1 | |
| SCHEMBL7459555 | 0.86 | MCHR1 (0.86) | MCHR1CACNA1GCHRM4CCR3CCR1 | |
| SCHEMBL7465416 | 0.86 | MCHR1 (0.78) | MCHR1CACNA1GKCNH2CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL7461498 | 0.85 | MCHR1 (0.87) | MCHR1CACNA1GCHRM4DRD2CCR3 | |
| Hydrochloric Acid SCHEMBL7466646 | 0.85 | MCHR1 (0.81) | MCHR1CHRM4DRD2CCR3CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |