Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 8/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8742873 | 0.99 | OXTR (0.40) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| Water SCHEMBL8742871 | 0.99 | OXTR (0.40) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| SCHEMBL7477344 | 0.93 | PTGDR2 (0.40) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| SCHEMBL8742798 | 0.93 | MAPT (0.39) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| SCHEMBL7468992 | 0.91 | MAPT (0.37) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| SCHEMBL7471675 | 0.89 | OXTR (0.43) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| Trifluoroacetic Acid SCHEMBL8590013 | 0.86 | OXTR (0.40) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| SCHEMBL7462162 | 0.81 | MAPT (0.39) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| SCHEMBL8742799 | 0.76 | MAPT (0.45) | OXTRAVPR1AMAPTTP53PTGDR2 | |
| SCHEMBL7476933 | 0.76 | PTGDR2 (0.46) | OXTRAVPR1AMAPTTP53PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |