Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783310 | 0.87 | PKM (0.36) | PKMSMN1; SMN2CYP4Z1TRPV1LMNA | |
| SCHEMBL7460913 | 0.79 | SNCA (0.47) | CA1CA2TSHRALDH1A1CYP3A4 | |
| SCHEMBL7826173 | 0.77 | CA1 (0.38) | PKMSMN1; SMN2CA1CA2TSHR | |
| SCHEMBL3779761 | 0.76 | CYP3A4 (0.38) | PKMSMN1; SMN2TSHRALDH1A1NPSR1 | |
| SCHEMBL10525761 | 0.75 | TDP1 (0.47) | PKMSMN1; SMN2CASP1TDP1CYP4F2 | |
| SCHEMBL31427174 | 0.74 | TDP1 (0.46) | PKMSMN1; SMN2CASP1TDP1CYP4F2 | |
| SCHEMBL20725247 | 0.74 | CYP4F2 (0.53) | PKMSMN1; SMN2CASP1TDP1CYP4F2 | |
| SCHEMBL250955 | 0.73 | TDP1 (0.68) | PKMSMN1; SMN2CASP1TDP1TRPV1 | |
| SCHEMBL9634242 | 0.73 | CNR2 (0.43) | SMN1; SMN2CA1CA2TSHRALDH1A1 | |
| SCHEMBL3783318 | 0.73 | CA12 (0.59) | SMN1; SMN2LMNACA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |