SCHEMBL7463571

SCHEMBL7463571

C=CCOC(=O)c1ccccc1C=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.74
TSHR P16473 4/20 0.64
ALDH1A1 P00352 3/20 0.64
HSD17B10 Q99714 1/20 0.64
RHOA P61586 1/20 0.44
LIG1 P18858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
ERN1 O75460 1/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SNCA P37840 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551356 0.88 CYP3A4 (0.77) CYP3A4TSHRALDH1A1HSD17B10RHOA
SCHEMBL16371573 0.86 CYP3A4 (1.00) CYP3A4TSHRALDH1A1HSD17B10RHOA
SCHEMBL27474785 0.86 CYP3A4 (1.00) CYP3A4TSHRALDH1A1HSD17B10RHOA
SCHEMBL15174 0.86 CYP3A4 (1.00) CYP3A4TSHRALDH1A1HSD17B10RHOA
SCHEMBL29362146 0.86 CYP3A4 (1.00) CYP3A4TSHRALDH1A1HSD17B10RHOA
SCHEMBL1696561 0.85 CYP3A4 (0.83) CYP3A4TSHRALDH1A1HSD17B10RHOA
Formic Acid SCHEMBL28100783 0.84 CYP3A4 (0.89) CYP3A4TSHRALDH1A1HSD17B10RHOA
SCHEMBL11394446 0.84 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10RHOA
SCHEMBL11394440 0.84 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10RHOA
Ethylene SCHEMBL11883084 0.84 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10RHOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5201920-A None JP disclosed
US-10042291-B2 Intermediate transfer member, image forming apparatus and image forming method Konica Minolta, Inc. (JP) 2018-08-07 US disclosed
US-20170357191-A1 INTERMEDIATE TRANSFER MEMBER, IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2017-12-14 US disclosed
US-20150378282-A1 TRANSFER MEMBER AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2015-12-31 US disclosed
US-9173395-B2 Use of substituted isoquinolinones, isoquinolindiones, isoquinolintriones and dihydroisoquinolinones or in each case salts thereof as active agents against abiotic stress in plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-11-03 US disclosed
US-20140302987-A1 USE OF SUBSTITUTED ISOQUINOLINONES, ISOQUINOLINDIONES, ISOQUINOLINTRIONES AND DIHYDROISOQUINOLINONES OR IN EACH CASE SALTS THEREOF AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-10-09 US disclosed
EP-0795548-B1 QUINAZOLINE DERIVATIVES AND USE THEREOF SUNTORY LTD (JP) 2002-07-03 EP disclosed
US-5814631-A CHYMASE INHIBITOR, CARDIVASCULAR SUNTORY LIMITED (JP) 1998-09-29 US disclosed
EP-0795548-A1 QUINAZOLINE DERIVATIVES AND USE THEREOF SUNTORY LIMITED (JP) 1997-09-17 EP disclosed
EP-0581024-B1 Polyester compounds and organic gelling agents comprising same NEW JAPAN CHEM CO LTD (JP) 1997-04-02 EP disclosed
US-5356566-A Polyester compounds and organic gelling agents comprising same NEW JAPAN CHEMICAL CO., LTD. (JP) 1994-10-18 US disclosed
EP-0581024-A1 Polyester compounds and organic gelling agents comprising same NEW JAPAN CHEMICAL CO.,LTD. (JP) 1994-02-02 EP disclosed
JP-H05201920-A PRODUCTION OF FORMYLBENZOIC ACID TEIJIN LTD 1993-08-10 JP disclosed
US-4133801-A Process for the preparation of polyesters TEIJIN LIMITED (JP) 1979-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140302987-A1 USE OF SUBSTITUTED ISOQUINOLINONES, ISOQUINOLINDIONES, ISOQUINOLINTRIONES AND DIHYDROISOQUINOLINONES OR IN EACH CASE SALTS THEREOF AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS NQO1, NFE2, NDUFS1 CYP3A4 391/4885TSHR 4501/4885ALDH1A1 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.