Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 18/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788016 | 0.87 | FLT1 (0.52) | FLT1FLT4KDR | |
| SCHEMBL7528058 | 0.85 | FLT1 (0.61) | GRIK1FLT1FLT4KDR | |
| SCHEMBL7519096 | 0.80 | HRH3 (0.56) | GRIK1 | |
| SCHEMBL3802745 | 0.79 | GRIK1 (0.47) | GRIK1FLT1FLT4KDRDUSP26 | |
| SCHEMBL7522905 | 0.79 | GRIK1 (0.50) | GRIK1 | |
| SCHEMBL7559587 | 0.79 | GRIK1 (0.66) | GRIK1 | |
| SCHEMBL7525043 | 0.78 | GRIK1 (0.46) | GRIK1FLT1FLT4KDRDUSP26 | |
| SCHEMBL7531464 | 0.78 | GRIK1 (0.56) | GRIK1 | |
| SCHEMBL6713098 | 0.76 | KDM1A (0.68) | DUSP26 | |
| SCHEMBL31310442 | 0.75 | FLT1 (0.83) | FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |