Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 18/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469556 | 0.89 | TP53 (0.46) | GRIK1ALDH1A1 | |
| SCHEMBL7528058 | 0.79 | FLT1 (0.61) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7463645 | 0.79 | GRIK1 (0.54) | GRIK1 | |
| SCHEMBL7559587 | 0.75 | GRIK1 (0.66) | GRIK1 | |
| SCHEMBL7531464 | 0.74 | GRIK1 (0.56) | GRIK1 | |
| SCHEMBL7519096 | 0.72 | HRH3 (0.56) | GRIK1MEN1KMT2A | |
| SCHEMBL7469874 | 0.71 | GRIK1 (0.51) | GRIK1 | |
| SCHEMBL3802745 | 0.71 | GRIK1 (0.47) | GRIK1 | |
| SCHEMBL7525043 | 0.70 | GRIK1 (0.46) | GRIK1 | |
| SCHEMBL7523406 | 0.70 | GRIK1 (0.54) | GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |