Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855288 | 0.81 | KMT2A (0.54) | KMT2AALDH1A1GAAHPGDL3MBTL1 | |
| SCHEMBL14186810 | 0.80 | NPSR1 (0.41) | NPSR1F2KMT2AALDH1A1KDM4E | |
| SCHEMBL6856109 | 0.77 | TDP1 (0.42) | KMT2AALDH1A1KDM4EMEN1L3MBTL1 | |
| SCHEMBL18572717 | 0.75 | NPSR1 (0.60) | NPSR1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL28478763 | 0.72 | NPSR1 (0.50) | NPSR1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL9461176 | 0.70 | KDM4E (0.53) | NPSR1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL3172528 | 0.67 | NPSR1 (0.50) | NPSR1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL18420706 | 0.67 | NPSR1 (0.44) | NPSR1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL14434341 | 0.67 | NPSR1 (0.44) | NPSR1F2KMT2AALDH1A1KDM4E | |
| SCHEMBL23295551 | 0.67 | NPSR1 (0.40) | NPSR1F2KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |