Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784568 | 0.81 | KMT2A (0.54) | KMT2AHTTL3MBTL1ADORA2AADORA1 | |
| SCHEMBL7464075 | 0.81 | NPSR1 (0.41) | KMT2AHTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL352579 | 0.80 | CYP1A2 (0.54) | KMT2AHTTCYP1A2PDE4DGAA | |
| SCHEMBL9460596 | 0.74 | CYP1A2 (0.48) | KMT2AHTTCYP1A2PDE4DGAA | |
| SCHEMBL6029638 | 0.73 | KMT2A (0.75) | KMT2AHTTL3MBTL1ADORA2AADORA1 | |
| SCHEMBL15348456 | 0.72 | KMT2A (0.78) | KMT2AHTTL3MBTL1ADORA2AADORA1 | |
| SCHEMBL10689456 | 0.71 | KMT2A (0.44) | KMT2AHTTL3MBTL1ADORA2AADORA1 | |
| SCHEMBL4236039 | 0.71 | KMT2A (0.44) | KMT2AHTTL3MBTL1ADORA2AADORA1 | |
| SCHEMBL4827391 | 0.71 | CYP1A2 (0.48) | KMT2ACYP1A2PDE4DGAACA12 | |
| SCHEMBL20788191 | 0.71 | KMT2A (0.76) | KMT2AHTTL3MBTL1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |